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Burden of Pneumonia-Associated Hospitalizations
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2 2018
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Source: Chest. 153(2):427-437
Details:
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Alternative Title:Chest
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Personal Author:
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Description:BACKGROUND:
The epidemiology of pneumonia has likely evolved in recent years, reflecting an aging population, changes in population immunity, and socioeconomic disparities.
METHODS:
Using the National (Nationwide) Inpatient Sample, estimated numbers and rates of pneumonia-associated hospitalizations for 2001–2014 were calculated. A pneumonia-associated hospitalization was defined as one in which the discharge record listed a principal diagnosis of pneumonia or a secondary diagnosis of pneumonia if the principal diagnosis was respiratory failure or sepsis.
RESULTS:
There were an estimated 20,361,181 (SE, 95,601) pneumonia-associated hospitalizations in the United States during 2001–2014 (average annual age-adjusted pneumonia- associated hospitalization rate of 464.8 per 100,000 population [95% CI, 462.5–467.1]). The average annual age-adjusted pneumonia-associated hospitalization rate decreased over the study period (P < .0001). In-hospital death occurred in 7.4% (SE, 0.03) of pneumonia-associated hospitalizations. Non-Hispanic American Indian/Alaskan Natives and non- Hispanic blacks had the highest average annual age-adjusted rates of pneumonia-associated hospitalization of all race/ethnicities at 439.2 (95% CI, 415.9–462.5) and 438.6 (95% CI, 432.5–444.7) per 100,000 population, respectively. During 2001–2014, the proportion of pneumonia-associated hospitalizations colisting an immunocompromising condition increased from 18.7% (SE, 0.2) in 2001 to 29.9% (SE, 0.2) in 2014. Total charges for pneumonia-associated hospitalizations in 2014 were over $84 billion.
CONCLUSIONS:
Pneumonia is a major cause of morbidity and mortality in the United States. Differences in rates and outcomes of pneumonia-associated hospitalizations between sociodemographic groups warrant further investigation. The immunocompromised population has emerged as a group experiencing a disproportionate burden of pneumonia-associated hospitalizations.
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Source:
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Pubmed ID:29017956
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Pubmed Central ID:PMC6556777
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Funding:
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Volume:153
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Issue:2
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