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AMYOTROPHIC LATERAL SCLEROSIS SURVEILLANCE IN BALTIMORE AND PHILADELPHIA
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6 2015
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Source: Muscle Nerve. 51(6):815-821
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Alternative Title:Muscle Nerve
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Description:Introduction
Limited epidemiological data on amyotrophic lateral sclerosis (ALS) exist in defined geographic areas in the United States.
Methods
Neurologists submitted case reports for patients under their care between January 1, 2009, and December 31, 2011, who met the El Escorial criteria. Diagnosis was confirmed for a sample of cases by the consulting neurologist. Death certificate data were used for supplemental case identification.
Results
The 248 reported cases were most likely to be 50–69 years old, men, white, and non-Hispanic. The total crude average annual incidence rate was 1.46 per 100,000 person-years.
Conclusions
The reported demographic characteristics were consistent with previously published findings. The crude annual incidence was slightly lower than the expected rate of 1.6 but was within the range reported previously (0.7–2.5). These findings help quantify the burden of ALS in the United States.
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Pubmed ID:25298019
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Pubmed Central ID:PMC4535347
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Volume:51
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Issue:6
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