Details:

• Alternative Title:
  Cancer Epidemiol Biomarkers Prev
• Personal Author:
  Melkonian, Stephanie C. ; Jim, Melissa A. ; Haverkamp, Donald ; Lee, Madeleine ; Janitz, Amanda E. ; ... More +

  Melkonian, Stephanie C. ; Jim, Melissa A. ; Haverkamp, Donald ; Lee, Madeleine ; Janitz, Amanda E. ; Campbell, Janis E. Less -
• Description:
  Background
  
  Non-Hispanic American Indian and Alaska Native (NH-AI/AN) people experience a disproportionate incidence of kidney cancer. Nationally aggregated data does not allow for a comprehensive description of regional disparities in kidney cancer incidence among NH-AI/AN communities. This study describes kidney cancer incidence rates and trends among NH-AI/AN compared to non-Hispanic White (NHW) populations by geographic region.
  
  Methods
  
  Using the United States Cancer Statistics American Indian and Alaska Native (AI/AN) Incidence Analytic Database, we calculated age-adjusted incidence rates (per 100,000) of kidney cancers for NH-AI/AN and NHW people for the years 2011–2020 combined using SEER*stat software. Analyses were restricted to non-Hispanic persons living in purchased/referred care delivery area (PRCDA) counties. Average annual percent changes (AAPCs) and trends (1999–2019) were estimated using Joinpoint regression analyses.
  
  Results
  
  Rates of kidney cancer incidence were higher among NH-AI/AN compared to NHW persons in the U.S. overall and in 5 of 6 regions. Kidney cancer incidence rates also varied by region, sex, age, and stage of diagnosis. Between 1999 and 2019, trends in rates of kidney cancer significantly increased among NH-AI/AN males (AAPC = 2.7%) and females (AAPC = 2.4%). The largest increases in incidence were observed for NH-AI/AN males and females under age 50 and those diagnosed with localized stage disease.
  
  Conclusions
  
  Study findings highlight growing disparities in kidney cancer incidence rates between NH-AI/AN and NHW populations.
  
  Impact:
  
  Differences in geographic region, sex, and stage highlight opportunities to decrease prevalence of kidney cancer risk factors and improve access to preventive care.
  
  
• Subjects:
  [+]

  Adult Aged Alaska Natives American Indian Or Alaska Native Female Humans Incidence Indians, North American Kidney Neoplasms Male Middle Aged SEER Program United States Young Adult
• Keywords:
  [+]

  Alaska Native American Indian Health Disparity Kidney Cancer Incidence
• Source:
  Cancer Epidemiol Biomarkers Prev. 33(8):1065-1072
• Pubmed ID:
  38727561
• Pubmed Central ID:
  PMC11293958
• Document Type:
  Journal Article
• Funding:
  CC999999/ImCDC/Intramural CDC HHSUnited States/ ; NA/Centers for Disease Control and Prevention (CDC)/

  CC999999/ImCDC/Intramural CDC HHSUnited States/ ; NA/Centers for Disease Control and Prevention (CDC)/ Less -
• Volume:
  33
• Issue:
  8
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  [+]

  urn:sha-512:d19addf6e27b3b306132bb995512b4b3e86bbe3d5310e68ffe061db7b0ff77865ff83b76aa85002bee4540e4850227511f17b9cb8593ab4bf63b8ab2b3b11e60
• File Type:

• Supporting Files:
  No Additional Files