Diphtheria antitoxin levels in the Netherlands: a population-based study.

de Melker, H. E.; Berbers, G. A.; Nagelkerke, N. J.; Conyn-van Spaendonck, M. A.

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Diphtheria antitoxin levels in the Netherlands: a population-based study.

1999 Sep-Oct
By de Melker, H. E. ; Berbers, G. A. ; Nagelkerke, N. J. ; ...
Source: Emerg Infect Dis. 5(5):694-700.

[PDF-124.03 KB]

English

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Details:

Alternative Title:

Emerg Infect Dis
Personal Author:

de Melker, H. E. ; Berbers, G. A. ; Nagelkerke, N. J. ; Conyn-van Spaendonck, M. A.

de Melker, H. E. ; Berbers, G. A. ; Nagelkerke, N. J. ; Conyn-van Spaendonck, M. A. Less -
Description:

In a population-based study in the Netherlands, diphtheria antitoxin antibodies were measured with a toxin-binding inhibition assay in 9, 134 sera from the general population and religious communities refusing vaccination. The Dutch immunization program appears to induce long-term protection against diphtheria. However, a substantial number of adults born before the program was introduced had no protective diphtheria antibody levels. Although herd immunity seems adequate, long-term population protection cannot be assured. As more than 60% of orthodox reformed persons have antibody levels lower than 0.01 IU/ml, introduction of diphtheria into religious communities refusing vaccination may constitute a danger of spread of the bacterium.
Subjects:

[+]

Adolescent Adult Aged Age Distribution Antibodies, Bacterial Child Child, Preschool Diphtheria Diphtheria Antitoxin Diphtheria Toxoid Female Humans Infant Male Middle Aged Population Surveillance Sex Distribution
Source:

Emerg Infect Dis. 5(5):694-700.
Document Type:

Journal Article
Place as Subject:

Netherlands
Volume:

5
Issue:

5
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

[+]

urn:sha256:dbfdab4c90f44f2454d090a5c4b27b1c87a76f0bc7a0cbe7b01146645b0f7d46
Download URL:

https://stacks.cdc.gov/view/cdc/14904/cdc_14904_DS1.pdf
File Type:

	10511526.nxml	txt
	license.txt	txt

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